Republican Charles Djou won the Hawaii seat belonging to the Dems since who knows when. I would caution against reading too much into this because, as frequently happens in three-way elections, the least popular candidate won.
Djou took 40%, and two other Dems split up 60% of the vote. Had either one of the Dems stepped aside, the seat would most likely have remained Democratic. The good news is that the Dems are about $300K poorer for having given away the seat, and Djou will have the advantages of incumbency when he has to defend the seat again this November.